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Although slightly inconspicuous from the outside, the Gemäldegalerie Alte Meister in the Semper wing of the Zwinger contains one of the world's greatest collections of art. Covering three floors, the gallery contains a host of 14th-18th Century paintings by masters such as Canaletto, Rubens, Dürer, Holbein and Rembrandt. But the highlight is clearly Raphael's Sistine Madonna portraying Mother and Child among the clouds, reproductions of which hang in hundreds of thousands of living rooms throughout the world.